What if one of the most commonly misdiagnosed conditions in eye care was also the easiest to detect? It only takes three seconds!
At the slit lamp, set magnification to 10–16X.1 Ask your patients to look down and examine the upper lid margin.1
Collarettes – the pathognomonic sign of Demodex blepharitis – can often go unnoticed.2,3
Finding collarettes at the lash base can help differentiate Demodex blepharitis and support faster, more accurate identification.
Transcript
0:05 – What if one of the most commonly missed diagnosis in eye care was also the easiest to detect?
0:11 – It’s just three seconds away at 10 to 16X magnification through a slit lamp.
0:17 – For many clinicians, diagnosing Demodex blepharitis still means plucking lashes and examining them under a microscope.
0:24 – That may work for clinical trials, but not when you’ve got 30 patients waiting and you’re already an hour behind.
0:30 – The process is uncomfortable for patients, time consuming for staff, and rarely fits into the daily clinical workflow.
0:37 – In my early years of practice, Demodex simply wasn’t on the radar.
0:42 – It wasn’t something we worked out to look for routinely and the diagnostic tools felt inpractical for the pace of a standard clinic.
0:50 – The emphasis was on other causes of the emerging disease, so unless a patient had very obvious signs, Demodex wasn’t even part of the differential.
1:00 – That mindset stuck with me longer than it should have…
1:04 – But even today many clinicians miss Demodex blepharitis due to a few small but critical oversights.
1:10 – Not asking the patient to look down. Not examining the upper lid margin.
1:15 – Without a look down maneuver and the magnification properly adjusted, collarettes on the upper lid margin often go unnoticed.
1:23 – For me, the shift came when I started integrating upper lid margin examination into my routine slit lamp workflow.
1:30 – I had a patient with persistent ocular surface symptoms that didn’t improve despite standard management approaches.
1:37 – I happened to ask them to look down and that’s when I saw it: clear collarettes along the upper lash line.
1:44 – It was an A-HA! moment.
1:46 – Once I began looking intentionally, I started finding Demodex far more often than I expected.
1:52 – It made me realize that I had likely been missing the true etiology in a significant portion of my chronic blepharitis patients suddenly.
1:59 – Collarettes are cylindrical, waxy debris of mite waste products and eggs found at the base of the eyelashes and can be identified during a routine slit lamp exam.
2:11 – The presence of collarettes alone is a pathognomonic sign of Demodex blepharitis.
2:16 – The Demodex Expert Panel on Treatment and Eyelid Health, or DEPTH, has classified Demodex blepharitis as a chronic, recurrent condition that may be under diagnosed in routine eye care, and prevalence data backs it up.
2:30 – Regardless of the initial reason for their visit to an eye care clinic.
2:34 – In the US, 58% of patients show signs of Demodex infestation.
2:39 – In Japan, the number climbs to 66%.
2:42 – Across Europe, 54% of patients screened show signs of Demodex blepharitis.
2:48 – It’s common, but underdiagnosed.
2:52 – Demodex blepharitis often presents with symptoms that mimic dry eye, meibomian gland dysfunction, or ocular allergies.
2:58 – Itching, irritation, and discomfort are common but non-specific.
3:03 – That overlap can lead to misclassification and delayed care.
3:07 – That’s why visual confirmation matters.
3:09 – Finding collarettes, or waxy sleeves around the lash base, can help differentiate DB from other conditions.
3:16 – Recognizing these signs during a slit lamp exam leads to faster, more accurate identification.
3:21 – Slit lamp diagnosis is quick and easy.
3:24 – Incorporating a simple look down maneuver and examining the upper lid margin at 10-16x magnification has significantly improved.
3:33 – It’s now a standard part of my anterior segment exam.
3:37 – I found that I identified Demodex much earlier, especially in patients presenting with non-specific irritation or lid margin disease that mimics MGD or allergy.
3:47 – This has allowed me to better tailor my management strategies and set more realistic expectations with patients.
3:54 – It also reduced frustration for both the patient and the practice, because we are not cycling through ineffective treatments before identifying the root cause.
4:01 – Ask the patient to look down.
4:05 – Set magnification to 10 to 16x.
4:08 – Examine the upper lash line.
4:10 – In just three seconds, you can confirm what was once easy to miss.
4:14 – This approach takes seconds and fits easily into any eye exam.
4:23 – Demodex blepharitis is easy to miss but even easier to confirm.
4:28 – Make this your new routine.
4:30 – Ask every patient. Every time.
4:33 – Look down. Screen for collarettes.
4:36 – Make the diagnosis.